McDonald 1974

The circulatory system allows us to transport nutrients, gases, blood cells, etc. to different organs. This fundamental task is achieved by a network of different blood vessels that distributes blood to all the cells.
Research in the hemodynamics requires a multidisciplinary approach that spans from medical to biological and fluid mechanics. Several pathologies affect the cardiovascular system, ranging from hypertension to aortic dissection, from aneurysm formation and development to atherosclerosis, with important connection to the hemodynamics and biomechanics. At the same time the establishment of a pathology determines important changes in the local, and then global, flow conditions. With the aim of studying the connections between the pre-existent conditions and the development of arterial pathologies several mathematical models has been developed. We develope both zero and one-dimensional models accounting for the entire arterial circulation.


Very important aspects concern the modelling of the structural properties of the vessel walls (and the connection with pathologies), the physiologically based distal boundary conditions, the heart modelling and his connection with the vessel network, the coronary circulation models, etc. without losing sight neither on the needed data nor on the physiological meaning.

We cooperate with the Hypertension Center of the Molinette University Hospital of Torino, directed by Professor Franco Veglio, in order to address a mixed medical-engineer multi-sectorial approach that is fundamental for the research in this field and has provided us with hige amount of physiological and pathological data on hypertension.

The main research interests can be listed as: hypertension, arterial and heart remodelling, ageing, aortic dissection, aneurysm formation, life-style induced cardiovascular effects.


List of Pubblications

More information: Carlo Camporeale